{"id":317,"date":"2021-01-11T11:25:24","date_gmt":"2021-01-11T10:25:24","guid":{"rendered":"https:\/\/sonofirst-trial.eu\/presentation-de-sonofirst\/"},"modified":"2021-06-22T12:27:34","modified_gmt":"2021-06-22T10:27:34","slug":"sonofirst-presentation","status":"publish","type":"page","link":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/","title":{"rendered":"Sonofirst presentation"},"content":{"rendered":"<p><strong>European Phase II randomised, open-label, multi-centre project<\/strong><\/p>\n<p>ClinicalTrials.gov Identifier: NCT04614493: <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04614493\">https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04614493<\/a><\/p>\n<p><strong>Number of patients:<\/strong> 66 participants<\/p>\n<p><strong>Treatment :<\/strong><\/p>\n<ul>\n<li><strong>Experimental arm:<\/strong> Patients receiving standard reference treatment (Stupp Protocol: surgery, focal radiotherapy, chemotherapy with temozolomide) with ultrasound from the SC9 device. Patients will be implanted with the SC9 device.<\/li>\n<li><strong>Reference arm:<\/strong> Patients receiving the reference treatment (Protocol Stupp: surgery, focal radiotherapy, chemotherapy with temozolomide) without ultrasound. There will be no implantation of the SC9 device.<\/li>\n<\/ul>\n<p><strong>Study duration:<\/strong> 30 months<\/p>\n<p><strong>Inclusion period:<\/strong> 12 months<\/p>\n<p><strong>Study start date:<\/strong> June 2021<\/p>\n<p><strong>Expected study completion date:<\/strong> December 2023<\/p>\n<p><strong>Duration of participation:<\/strong> 18 months (last patient), up to 30 months for 1st patient included<\/p>\n<p><strong>Primary objective:<\/strong> Clinical efficacy based on comparison of median PFS (progression-free survival) assessed by the local investigator between standard of care treatment with ultrasound BBB opening and standard of care treatment alone.<\/p>\n<p><strong>Number of recruiting sites:<\/strong> 7 of which 5 in France, 1 in Belgium and 1 in Switzerland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>European Phase II randomised, open-label, multi-centre project ClinicalTrials.gov Identifier: NCT04614493: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04614493 Number of patients: 66 participants Treatment : Experimental arm: [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-317","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sonofirst presentation - SonoFirst<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sonofirst presentation - SonoFirst\" \/>\n<meta property=\"og:description\" content=\"European Phase II randomised, open-label, multi-centre project ClinicalTrials.gov Identifier: NCT04614493: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04614493 Number of patients: 66 participants Treatment : Experimental arm: [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/\" \/>\n<meta property=\"og:site_name\" content=\"SonoFirst\" \/>\n<meta property=\"article:modified_time\" content=\"2021-06-22T10:27:34+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/sonofirst-presentation\\\/\",\"url\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/sonofirst-presentation\\\/\",\"name\":\"Sonofirst presentation - SonoFirst\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/#website\"},\"datePublished\":\"2021-01-11T10:25:24+00:00\",\"dateModified\":\"2021-06-22T10:27:34+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/sonofirst-presentation\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/sonofirst-presentation\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/sonofirst-presentation\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sonofirst presentation\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/\",\"name\":\"SonoFirst\",\"description\":\"supported by the European Union\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sonofirst-trial.eu\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sonofirst presentation - SonoFirst","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/","og_locale":"en_US","og_type":"article","og_title":"Sonofirst presentation - SonoFirst","og_description":"European Phase II randomised, open-label, multi-centre project ClinicalTrials.gov Identifier: NCT04614493: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04614493 Number of patients: 66 participants Treatment : Experimental arm: [&hellip;]","og_url":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/","og_site_name":"SonoFirst","article_modified_time":"2021-06-22T10:27:34+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/","url":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/","name":"Sonofirst presentation - SonoFirst","isPartOf":{"@id":"https:\/\/sonofirst-trial.eu\/en\/#website"},"datePublished":"2021-01-11T10:25:24+00:00","dateModified":"2021-06-22T10:27:34+00:00","breadcrumb":{"@id":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/sonofirst-trial.eu\/en\/sonofirst-presentation\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/sonofirst-trial.eu\/en\/"},{"@type":"ListItem","position":2,"name":"Sonofirst presentation"}]},{"@type":"WebSite","@id":"https:\/\/sonofirst-trial.eu\/en\/#website","url":"https:\/\/sonofirst-trial.eu\/en\/","name":"SonoFirst","description":"supported by the European Union","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sonofirst-trial.eu\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/pages\/317","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/comments?post=317"}],"version-history":[{"count":0,"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/pages\/317\/revisions"}],"wp:attachment":[{"href":"https:\/\/sonofirst-trial.eu\/en\/wp-json\/wp\/v2\/media?parent=317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}